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Translational Research refers to a particular type of research primarily aimed to improve human health. This means using basic knowledge in biology, technology, physics (..) for clinical uses.

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BASIC overview of the translational path

ACCELERATE Potential | Â鶹´«Ã½ÊÓƵÍøÕ¾ School of Life and Medical Sciences - Â鶹´«Ã½ÊÓƵÍøÕ¾ – University College London. This online course is an introduction to the Translational Research and the Translational Path. Self paced, for Â鶹´«Ã½ÊÓƵÍøÕ¾ staff/studentsÌýand externals.

The Academic Careers Office (ACO) at Â鶹´«Ã½ÊÓƵÍøÕ¾ is part of the Office of the Vice Provost for Health (OVPH). The OVPH's mission is to enhanceÌýexternal relationships in biomedicine with a range of medical research organisations, NHS included. The ACOÌýpromotes, supports and develops many aspects of academicÌýin health related disciplines across Â鶹´«Ã½ÊÓƵÍøÕ¾. As Â鶹´«Ã½ÊÓƵÍøÕ¾ students and researchers at Â鶹´«Ã½ÊÓƵÍøÕ¾ Queen Square IoN, everyone is welcomed to use this resource.ÌýACCELERATE | Â鶹´«Ã½ÊÓƵÍøÕ¾ School of Life and Medical Sciences - Â鶹´«Ã½ÊÓƵÍøÕ¾ – University College London

ADVANCED overview of therapeutic development by modality: biologics, gene and cell therapy, devices and diagnostics, regenerative medicine, small molecule and repurposingo

Click on the modality you are interested to explore. Roadmaps:

-ÌýBiologics Translation Roadmap | Â鶹´«Ã½ÊÓƵÍøÕ¾ Therapeutic Innovation Networks - Â鶹´«Ã½ÊÓƵÍøÕ¾ – University College London
-ÌýCell & Gene Therapy Translation Roadmap | Â鶹´«Ã½ÊÓƵÍøÕ¾ Therapeutic Innovation Networks - Â鶹´«Ã½ÊÓƵÍøÕ¾ – University College London
-ÌýDevices Translation Roadmap | Â鶹´«Ã½ÊÓƵÍøÕ¾ Therapeutic Innovation Networks - Â鶹´«Ã½ÊÓƵÍøÕ¾ – University College London
-ÌýRegenerative Medicines Case Studies | Â鶹´«Ã½ÊÓƵÍøÕ¾ Therapeutic Innovation Networks - Â鶹´«Ã½ÊÓƵÍøÕ¾ – University College London
-ÌýSmall Molecules Translation Roadmap | Â鶹´«Ã½ÊÓƵÍøÕ¾ Therapeutic Innovation Networks - Â鶹´«Ã½ÊÓƵÍøÕ¾ – University College London Repurposing | Â鶹´«Ã½ÊÓƵÍøÕ¾ Therapeutic Innovation Networks - Â鶹´«Ã½ÊÓƵÍøÕ¾ – University College London

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Landing page:ÌýÂ鶹´«Ã½ÊÓƵÍøÕ¾ Therapeutic Innovations Networks (TINs) | Â鶹´«Ã½ÊÓƵÍøÕ¾ Therapeutic Innovation Networks - Â鶹´«Ã½ÊÓƵÍøÕ¾ – University College London.

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TheseÌýresources areÌýoffered by the Therapeutic Innovations Networks (TINs @Â鶹´«Ã½ÊÓƵÍøÕ¾). The TINsÌýis a specific framework embedded in the Translational Research Office (TRO)Ìýand partnered with NIHR Biomedical Research Centres (Â鶹´«Ã½ÊÓƵÍøÕ¾H, Great Ormond Street Hospital, Moorfields eye hospital) for education, training and outreach of early career researchers.

The TRO's main purpose is to support translational research at Â鶹´«Ã½ÊÓƵÍøÕ¾ Translational Research Office | Translational Research Office (TRO) - Â鶹´«Ã½ÊÓƵÍøÕ¾ – University College London.

Webinars:ÌýTIN Webinar Recordings | Â鶹´«Ã½ÊÓƵÍøÕ¾ Therapeutic Innovation Networks - Â鶹´«Ã½ÊÓƵÍøÕ¾ – University College London

FOCUS on the development pathway and regulations of gene, cell and tissue therapy (ATMPs: advanced therapy medical products)

Advanced therapy medicinal products (ATMPs) are medicines for human use that areÌýeitherÌýa gene therapy medicinal product, a somatic cell therapy medicinal product, orÌýÌýa tissue engineered product. Here you can find informativeÌýmaterial from the UK and EU regulatory agency.

- MHRA (UK):Ìý
- EMA (EU):Ìý, and alsoÌý
More webinars and material on ATMPs from London Advanced Therapies in collaboration with NHS

- After the initial registration, search for key words such as 'cell/gene therapy'Ìý
- Ìýseries of talks, case studies and tool kit

Talk by Prof Mark Lowdell (Â鶹´«Ã½ÊÓƵÍøÕ¾) on advancing ATMPs from academia to industryÌý

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FOCUS on the development pathway and regulations of small molecules and devices

This presentationÌýwas made by Deloitte and published by gov.uk* (2016) as aÌýguide to navigating the innovation pathway in England. It includes development pathways for pharmaceuticals and medical technologies.ÌýÌý(*The document is pre-Brexit, therefore some links are not anymore up to date or available. Check with the TRO/TRM if you have specific questions). -Ìý.

Oxford also offers some interesting webinars freely available:

Small molecule:Ìý. The University of Oxford offers a series of videos to discuss the experience of innovators from pharma (Bayers, Astra Zeneca), but also regulators. Click here you hear about target validation, regulation, commercialisation and investment opportunities.Ìý
Devices:Ìý. The development of a device follows different regulations compared to a biologic.ÌýIt is also good practice to have an idea of the category to which the device belongs.ÌýThe online tool RegMetrics is a digital platform to support health technology innovators in navigating the medical device regulations. The technology was initially developed by the Natural Interaction Lab () at the University of Oxford, as a solution for a need that was observed within the community of innovators.Ìý

IP (Intellectual property) - Â鶹´«Ã½ÊÓƵÍøÕ¾ resources

Â鶹´«Ã½ÊÓƵÍøÕ¾B (tech transfer office) follows any development for intellectual property establishment at Â鶹´«Ã½ÊÓƵÍøÕ¾.

- General policy:ÌýÂ鶹´«Ã½ÊÓƵÍøÕ¾ Intellectual Property (IP) Policy | Innovation & Enterprise - Â鶹´«Ã½ÊÓƵÍøÕ¾ – University College London
-ÌýCommercialisation of an IP and revenue sharing policy at Â鶹´«Ã½ÊÓƵÍøÕ¾:ÌýÂ鶹´«Ã½ÊÓƵÍøÕ¾ Revenue Sharing Policy | Innovation & Enterprise - Â鶹´«Ã½ÊÓƵÍøÕ¾ – University College London
-ÌýNon-patentable IP:Ìý

For any enquires see UCB Q&AÌýÌýor contact one of the Business Managers:Ìý,Ìý.Ìý

PPI (Patient and Public involvement)

Evidence of involving patients and the public in the planning, design, management and/or dissemination of research is increasingly a requirement of major funding bodies in the UK. Â鶹´«Ã½ÊÓƵÍøÕ¾ÌýprovideS an online PPI helpdesk that researchers can contact PatienceÌýfor advice on PPI. The helpdesk can be contacted onÌýppihelpdesk@ucl.ac.uk.

Other resources are:

- The JROÌýAbout |ÌýAbout | Joint Research Office - Â鶹´«Ã½ÊÓƵÍøÕ¾ – University College London
- The NIHR Â鶹´«Ã½ÊÓƵÍøÕ¾H Biomedical Research Centre runs a programme of regular workshops for researchers at Â鶹´«Ã½ÊÓƵÍøÕ¾ Partner organisations on patient and public involvement (PPI) in research.Ìý
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- Charities