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Drug Design and Development (PHAR0014)

Key information

Faculty
Faculty of Life Sciences
Teaching department
Division of Biosciences
Credit value
15
Restrictions
Some background in pharmacology or therapeutics is expected.
Timetable

Alternative credit options

There are no alternative credit options available for this module.

Description

This module is taught by the Faculty of Medicine and Life Sciences and is about the discovery of new drugs and therapies. Students will consider the ways of identifying novel compounds for development and the processes which take place before such compounds are released onto the market following its introduction into clinical practice. The module includes an opportunity for group project work on the development of a specific drug and series of case studies looking at the criteria which contributes to successful outcome in a drug development programme.听

On completion of the module, students will be able to:听

  • Explain how novel targets for drugs are identified and to give specific examples.听

  • Understand how novel compounds are screened for the desired activity and the limitations of such screening.听

  • Explain the objectives of pre-clinical evaluation of novel compounds for activity and toxicity.听

  • Know what information is desirable before a novel compound is first introduced into human subjects and to be able to explain the objectives of Phase I clinical studies, including pharmacokinetic and pharmacodynamic matters.听

  • Explain the design features of a valid clinical trial, including ethical considerations and statistical requirements.听

  • Understand the information needed to introduce a new drug into clinical practice, the function and operation of the licensing scheme and the arrangements for monitoring new drugs after their introduction.听

  • Give critical commentary on clinical trial data.听

  • Understand the strategic, scientific and operational criteria which contribute to a drug discovery programme.听

Indicative Lecture list听

  • Strategies for Drug Discovery听

  • Multi-Drug Resistance Proteins and Pharmacokinetics听

  • Anti-Angiogenic Drugs听

  • First in Human Studies听

  • Ethics of Human Experimentation听

  • Introduction to NICE听

  • Molecule to Medicine听

  • Identifying New Targets for Drug Action听

  • Animal Models听

  • Proactive Pharmacovigilance听

  • 罢辞虫颈肠辞濒辞驳测听

  • Clinical Trials听

  • New Drugs in the Clinic听

  • Case studies听

  • Innovation in Drug Discovery听

Module deliveries for 2024/25 academic year

Intended teaching term: Term 1 听听听 Undergraduate (FHEQ Level 7)

Teaching and assessment

Mode of study
In person
Methods of assessment
40% Viva or oral presentation
60% Coursework
Mark scheme
Numeric Marks

Other information

Number of students on module in previous year
6
Module leader
Dr Dean Willis
Who to contact for more information
dean.willis@ucl.ac.uk

Intended teaching term: Term 1 听听听 Postgraduate (FHEQ Level 7)

Teaching and assessment

Mode of study
In Person
Methods of assessment
40% Viva or oral presentation
60% Coursework
Mark scheme
Numeric Marks

Other information

Number of students on module in previous year
11
Module leader
Dr Dean Willis
Who to contact for more information
dean.willis@ucl.ac.uk

Intended teaching term: Term 1 听听听 Undergraduate (FHEQ Level 6)

Teaching and assessment

Mode of study
In Person
Methods of assessment
40% Group activity
60% Coursework
Mark scheme
Numeric Marks

Other information

Number of students on module in previous year
163
Module leader
Dr Dean Willis
Who to contact for more information
dean.willis@ucl.ac.uk

Last updated

This module description was last updated on 19th August 2024.

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Important information

The catalogue has been updated with key information about the modules that will run during the 2024/25 academic session. Current and prospective students can browse through the catalogue to consider possible module choices for the coming year.

Please note,听information in the catalogue is听subject to change as teaching and assessment arrangements for 2024/25 may need to be adjusted in line with the University's Feedback and Assessment principles and operating model.

Centrally managed exam durations will be provided on students' individual exam timetables. Arrangements for locally managed timed assessments and in-class activity will be confirmed by the teaching department for the module.

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